Follow us

Sample Preparation

The Chemistry Behind the Techniques

Come prepared to learn that sample preparation is more than just a few "low technology" procedures. Learn about the chemical principles behind the techniques, and how an understanding of these principles will provide better results. This course will include a survey of many traditional procedures, including information on recent advances in these techniques. Several new sample preparation technologies will also be introduced.

This is not a "recipe" course limited to a particular sample type or application. This course offers a comprehensive treatment of sample preparation as an important part of every analytical method. You will learn more than just a few manipulations; you will come away with a complete understanding of what sample preparation is and how you can use it effectively.

Students will realize the following benefits from this course:

  • Better control of variables in sample preparation steps, producing more reliable results.
  • Better efficiency and decision-making skills, since time is not wasted on unnecessary or lengthy manipulations
  • A knowledge of what traditional techniques are available, and what recent advances make them even more efficient.
  • An understanding of several "new" technologies that might also be useful.


  1. Perspectives on the Importance of Sample Preparation
  2. General Principles
    • Physical Changes, LeChatelier's Principle
    • Effects of Temperature, Time, Ionic Strength, and pH
    • "Like-Dissolves-Like"
    • Partitioning Equilibria
  3. Traditional Procedures
    • Derivatization
    • Filtration
    • Drying Agents
    • Solvent Evaporation
    • Solvent Exchange
  4. Traditional Techniques
    • Liquid-Liquid Extraction
      • Separatory funnels
      • Other LLE variations
      • Emulsions
    • Liquid-Solid Extraction
      • Soxhlet/Accelerated Soxhlets
      • Microwave-based methods
      • Ultrasonics
      • SPE
  5. New Technologies
    • Membrane Disk Extractions
    • GC Sample Preparation
    • Supercritical Fluid Extraction (SFE)
    • Solid Phase Microextraction (SPME)
    • Accelerated Solvent Extraction (ASE)

Course Length: 1 day

Sample Preparation "Plus":
Traditional Tools for Modern Labs

Working in pharma prep?
Only working with the traditional techniques?

We have a special presentation option that covers only Sections 1 - 4. You will get more detail on all of the traditional techniques, and more examples. This option includes an extensive discussion time at the end of the day, where you can discuss your own particular applications and problems.

Call today for more details:








Home Overview Best Practices Training Consulting Lab Life-Line Contact Us

ACCTA, Inc., 3534 Jessie Ct, St. Paul, MN 55125 USA
Phone: (651) 731-3670 Fax: (651) 730-0965
For information on contacting the webmaster, click here.
© ACCTA, Inc. All rights reserved.
This page last updated October, 2007.