Case Study #5
LC Method Development for a Complex Mixed Product
An existing LC method suffered from the following problems:
A representative chromatogram is shown below.
An efficient method was developed that easily separated the small molecule isomers and produced several characteristic peaks for the peptide mixture. The method even allowed quantification of a second peptide mixture that was present in other formulations.
The final procedure offered the following advantages:
See the difference in the following chromatogram.
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This page last updated February, 2009.